Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807645 | 0.89 | ALDH1A1 (0.51) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL7815153 | 0.85 | KDM4E (0.60) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL7817348 | 0.83 | MET (0.59) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL7806871 | 0.83 | ALDH1A1 (0.53) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL7820657 | 0.79 | KDM4E (0.61) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL7814851 | 0.76 | ALDH1A1 (0.60) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL7807153 | 0.74 | MAPT (0.48) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL3036231 | 0.73 | MAOB (0.54) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL7820367 | 0.73 | MET (0.50) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL9906888 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2POLBMAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |