Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436094 | 0.82 | SMN1; SMN2 (0.49) | MAPTHSD17B10CASP1METRPS6KA3 | |
| SCHEMBL7267666 | 0.82 | LMNA (0.49) | MAPTHSD17B10CASP1GLAHTT | |
| SCHEMBL7814851 | 0.80 | ALDH1A1 (0.60) | MAPTHSD17B10CASP1GLAHTT | |
| SCHEMBL4991019 | 0.79 | KDM4E (0.44) | MAPTHSD17B10CASP1GLAHTT | |
| SCHEMBL7817770 | 0.77 | MET (0.53) | MAPTHSD17B10CASP1GLAHTT | |
| SCHEMBL7814815 | 0.74 | ALDH1A1 (0.62) | MAPTHSD17B10CASP1GLACASP7 | |
| SCHEMBL7806871 | 0.74 | ALDH1A1 (0.53) | MAPTHSD17B10CASP1GLAMET | |
| SCHEMBL7806963 | 0.74 | SMN1; SMN2 (0.52) | MAPTHSD17B10CASP1METRPS6KA3 | |
| SCHEMBL7815167 | 0.74 | ALDH1A1 (0.62) | MAPTHSD17B10CASP1GLAHTT | |
| SCHEMBL4443241 | 0.74 | SMN1; SMN2 (0.49) | MAPTHSD17B10CASP1METRPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | claimed |
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |