Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996642 | 0.81 | ADRA2A (0.50) | LMNAEGLN1ALKBH5SUCNR1L3MBTL1 | |
| SCHEMBL1799780 | 0.81 | DGKA (0.39) | L3MBTL1TSHRADRA2AADRA1ATDP1 | |
| SCHEMBL3508243 | 0.79 | MGAM (0.43) | LMNAEGLN1ALKBH5SUCNR1L3MBTL1 | |
| SCHEMBL10838469 | 0.78 | ADRA2A (0.38) | ADRA2AADRA1ATDP1MAPTBLM | |
| SCHEMBL11431499 | 0.78 | ALDH1A1 (0.41) | LMNAL3MBTL1TSHRADRA2AADRA1A | |
| Ammonia Solution, Strong SCHEMBL11412539 | 0.77 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1L3MBTL1 | |
| SCHEMBL8442545 | 0.77 | ADRA2A (0.41) | LMNAEGLN1ALKBH5SUCNR1L3MBTL1 | |
| SCHEMBL3508245 | 0.77 | TSHR (0.41) | LMNAEGLN1ALKBH5SUCNR1L3MBTL1 | |
| SCHEMBL7817943 | 0.76 | TSHR (0.52) | LMNATSHRADRA2AADRA1AALDH1A1 | |
| SCHEMBL8979257 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5695909-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-12-09 | — | — | US | claimed |
| EP-1112268-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND HERBICIDES CONTAINING THEM | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015633-A1 | CONDENSED HETEROCYLIC COMPOUNDS AND HERBICIDES CONTAINING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-23 | — | — | WO | disclosed |
| US-5695909-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| US-5665887-A | Methine compound | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |