Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815533 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL7069265 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL7817846 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL7807177 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL6750239 | 0.78 | KMT2A (0.41) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL7806953 | 0.77 | CYP3A4 (0.36) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL7815723 | 0.76 | HSD17B10 (0.37) | ALDH1A1MAPTKMT2AMAPK1MEN1 | |
| SCHEMBL1808677 | 0.72 | PLA2G1B (0.52) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7072645 | 0.71 | GAA (0.35) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL7070729 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2AHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129083-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000029398-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-05-25 | — | — | WO | disclosed |