Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22796318 | 0.82 | EDNRA (0.40) | KMT2AMAPTHSD17B10TSHRNPSR1 | |
| SCHEMBL7955303 | 0.79 | ALDH1A1 (0.39) | KMT2AMAPTHSD17B10KDM4ENPC1 | |
| SCHEMBL6751984 | 0.79 | KDM4E (0.46) | KMT2AMAPTHSD17B10TSHRNPSR1 | |
| SCHEMBL7807244 | 0.78 | ALDH1A1 (0.46) | KMT2AMAPTHSD17B10TSHRNPSR1 | |
| SCHEMBL7072645 | 0.77 | GAA (0.35) | KMT2AMAPTHSD17B10TSHRNPSR1 | |
| SCHEMBL7253131 | 0.77 | ADORA2A (0.35) | RAB9A | |
| SCHEMBL13406688 | 0.77 | MAPT (0.40) | KMT2AMAPTHSD17B10TSHRNPSR1 | |
| SCHEMBL7088346 | 0.76 | SMN1; SMN2 (0.38) | KMT2AMAPTNPSR1KDM4ENPC1 | |
| SCHEMBL7088428 | 0.75 | ALDH1A1 (0.42) | MAPTHSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL1046379 | 0.74 | TRPM8 (0.37) | RAB9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874654-A | Pyran compound as plant immune activator and application thereof | 华东理工大学 | 2025-04-25 | — | — | CN | disclosed |
| US-20220000117-A1 | METHOD FOR CONTROLLING DISEASES IN SMALL GRAIN CEREALS, SEED OF SMALL GRAIN CEREALS, AND METHOD FOR SUPPRESSING LODGING DAMAGE IN SMALL GRAIN CEREALS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2022-01-06 | — | — | US | disclosed |
| EP-3878278-A1 | METHOD FOR CONTROLLING DISEASES IN SMALL GRAIN CEREALS, SEED OF SMALL GRAIN CEREALS, AND METHOD FOR SUPPRESSING LODGING DAMAGE IN SMALL GRAIN CEREALS | Kumiai Chemical Industry Co., Ltd. (JP) | 2021-09-15 | — | — | EP | disclosed |
| EP-3127902-B1 | METHOD FOR PRODUCING ISOTHIAZOLE COMPOUND USING ETHER COMPOUND | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2018-11-07 | — | — | EP | disclosed |
| CN-106458941-A | Method for producing isothiazole compound using ether compound | 庵原化学工业株式会社 | 2017-02-22 | — | — | CN | disclosed |
| EP-3127902-A1 | METHOD FOR PRODUCING ISOTHIAZOLE COMPOUND USING ETHER COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2017-02-08 | — | — | EP | disclosed |
| US-9353071-B2 | Method for manufacturing isothiazole compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150291540-A1 | METHOD FOR MANUFACTURING ISOTHIAZOLE COMPOUND | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-10-15 | — | — | US | disclosed |
| EP-2905280-A1 | METHOD FOR MANUFACTURING ISOTHIAZOLE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2015-08-12 | — | — | EP | disclosed |
| CN-104822667-A | Method for manufacturing isothiazole compound | IHARA CHEMICAL IND CO | 2015-08-05 | — | — | CN | disclosed |
| US-6706748-B2 | USE AS MICROBICIDES | NIHON BAYER AGROCHEM, K.K. (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20030220197-A1 | Isothiazole derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 2003-11-27 | — | — | US | disclosed |
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | NIHON BAYER AGROCHEM, K.K. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1284970-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-1261592-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001077090-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-18 | — | — | WO | disclosed |
| WO-2001055124-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000117-A1 | METHOD FOR CONTROLLING DISEASES IN SMALL GRAIN CEREALS, SEED OF SMALL GRAIN CEREALS, AND METHOD FOR SUPPRESSING LODGING DAMAGE IN SMALL GRAIN CEREALS | LCT, BROX, GYS2 | KMT2A 1315/4885MAPT 70/4885HSD17B10 991/4885 |
| US-20030220197-A1 | Isothiazole derivatives | IRF3, MSR1, ARG1 | KMT2A 3359/4885MAPT 4221/4885HSD17B10 2293/4885 |
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | IFNG, MPO, CD14 | KMT2A 1704/4885MAPT 4555/4885HSD17B10 2835/4885 |
| US-20150291540-A1 | METHOD FOR MANUFACTURING ISOTHIAZOLE COMPOUND | CBR3, CSNK1D, IDH3A | KMT2A 2104/4885MAPT 1622/4885HSD17B10 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.