Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16049307 | 0.81 | NPSR1 (0.37) | GAAPOLBNPSR1HSD17B10MAPT | |
| SCHEMBL26288500 | 0.78 | CA12 (0.38) | GAAPOLBNPSR1HSD17B10MAPT | |
| SCHEMBL9446207 | 0.77 | KDM4E (0.36) | GAANPSR1HSD17B10MAPTTSHR | |
| SCHEMBL6750239 | 0.77 | KMT2A (0.41) | POLBNPSR1HSD17B10MAPTTSHR | |
| SCHEMBL16049254 | 0.72 | L3MBTL1 (0.51) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL7807244 | 0.71 | ALDH1A1 (0.46) | GAANPSR1HSD17B10MAPTTSHR | |
| SCHEMBL1720501 | 0.71 | — | — | |
| SCHEMBL28048586 | 0.70 | — | — | |
| SCHEMBL3406573 | 0.69 | ALDH1A1 (0.47) | GAAPOLBNPSR1HSD17B10MAPT | |
| SCHEMBL14794771 | 0.68 | PRKCZ (0.47) | MAPTKMT2AKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552056-B2 | Bactericides; fungicides; miticides; nematocides; for agriculture | NIHON BAYER AGROCHEM K.K. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20030013750-A1 | Isothiazolecarboxamides and their use as microbicides | NIHOM BAYER AGROCHEM K.K. (JP) | 2003-01-16 | — | — | US | disclosed |
| CN-1353700-A | Isothiazole carboxamides and their use as microbicides | BAYER AGROCHEM KK (JP) | 2002-06-12 | — | — | CN | disclosed |
| EP-1185519-A1 | ISOTHIAZOLECARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000073290-A1 | ISOTHIAZOLECARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013750-A1 | Isothiazolecarboxamides and their use as microbicides | MCL1, MSR1, MPO | GAA 3627/4885POLB 2701/4885NPSR1 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.