Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071481 | 0.87 | ANO1 (0.37) | ALDH1A1HTTSMN1; SMN2KMT2AANO1 | |
| SCHEMBL7807244 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL7069265 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL7817846 | 0.69 | ALDH1A1 (0.48) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL7807177 | 0.68 | ALDH1A1 (0.49) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL7214349 | 0.67 | POLB (0.47) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8443773 | 0.64 | ALDH1A1 (0.57) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL7213661 | 0.63 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2AANO1 | |
| SCHEMBL7213607 | 0.63 | POLB (0.49) | ALDH1A1SMN1; SMN2KMT2ALMNAKDM4E | |
| SCHEMBL7220101 | 0.62 | HPGD (0.46) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552056-B2 | Bactericides; fungicides; miticides; nematocides; for agriculture | NIHON BAYER AGROCHEM K.K. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20030013750-A1 | Isothiazolecarboxamides and their use as microbicides | NIHOM BAYER AGROCHEM K.K. (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-1185519-A1 | ISOTHIAZOLECARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000073290-A1 | ISOTHIAZOLECARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013750-A1 | Isothiazolecarboxamides and their use as microbicides | MCL1, MSR1, MPO | ALDH1A1 591/4885HTT 4639/4885SMN1; SMN2 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.