SCHEMBL780745

SCHEMBL780745

CO[C@@H]1[C@H](O)[C@@H](CO[Si](C)(C)C(C)(C)C)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.56
P2RY2 P41231 11/20 0.50
P2RY6 Q15077 9/20 0.50
P2RY4 P51582 6/20 0.50
P2RY14 Q15391 5/20 0.50
SLC28A1 O00337 1/20 0.50
SLC28A2 O43868 1/20 0.50
SLC29A1 Q99808 1/20 0.50
SLC28A3 Q9HAS3 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780746 1.00 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL21089723 1.00 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL25399227 1.00 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL18858899 0.93 DUT (0.53) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL6760952 0.92 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL24782135 0.92 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL26373405 0.92 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL24781265 0.92 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL10391187 0.92 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14
SCHEMBL26373418 0.92 DUT (0.56) DUTP2RY2P2RY6P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS TRILINK BIOTECHNOLOGIES, LLC 2025-06-26 US disclosed
EP-4499824-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2025-02-05 EP disclosed
WO-2023183569-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2023-09-28 WO disclosed
US-20120070411-A1 SUBSTITUTED NUCLEOTIDE ANALOGS ALIOS BIOPHARMA, INC. (US) 2012-03-22 US disclosed
US-6822090-B2 GENERATION OF PREFERENTIAL URIDINE DERIVATIVE; OBTAIN REACTION MIXTURE, EXPOSE TO TERTIARY AMINE, DEHYDRATING REACTANT AND AMMONIA, RECOVER CYTIDINE DERIVATIVE MITSUI CHEMICALS, INC. (JP) 2004-11-23 US disclosed
US-20030032797-A1 Process for the preparation of cytidine derivatives MITSUI CHEMICALS, INC. (JP) 2003-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032797-A1 Process for the preparation of cytidine derivatives CDA, DCTD, APOBEC3A DUT 15/4885P2RY2 3374/4885P2RY6 2224/4885
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS RNGTT, POLRMT, POLN DUT 8/4885P2RY2 3188/4885P2RY6 2972/4885
US-20120070411-A1 SUBSTITUTED NUCLEOTIDE ANALOGS PNP, NTPCR, NUDT1 DUT 17/4885P2RY2 101/4885P2RY6 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.