SCHEMBL7807476

SCHEMBL7807476

CN(CCO)c1ccc(N)c(-c2ccc[nH]2)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.34
STK4 Q13043 1/20 0.32
STK3 Q13188 1/20 0.32
LRRK2 Q5S007 1/20 0.32
EGFR P00533 1/20 0.31
APP P05067 1/20 0.31
MAPT P10636 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7808744 0.86 MAPT (0.36) L3MBTL1MAPTADORA2A
SCHEMBL7808518 0.84 CYP3A4 (0.33)
SCHEMBL7812289 0.82
SCHEMBL7800962 0.81 ALDH1A1 (0.38) APPMAPTADORA2A
SCHEMBL6573339 0.79 L3MBTL1 (0.43) MAP4K4L3MBTL1STK4STK3LRRK2
SCHEMBL7805944 0.76 ALDH1A1 (0.33) MAP4K4STK4STK3LRRK2MAPT
SCHEMBL7461069 0.76 MAP4K4 (0.34) MAP4K4L3MBTL1STK4STK3LRRK2
SCHEMBL7808809 0.75 S100B (0.32) MAP4K4
SCHEMBL7807501 0.74 CDK2 (0.30)
SCHEMBL7812056 0.73 CFTR (0.39) MAP4K4L3MBTL1MAPTADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed