Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 5/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808518 | 0.88 | CYP3A4 (0.33) | — | |
| SCHEMBL7808744 | 0.82 | MAPT (0.36) | S100BCDK2 | |
| SCHEMBL7800962 | 0.77 | ALDH1A1 (0.38) | CDK2CLK4 | |
| SCHEMBL7462136 | 0.76 | CYP1A2 (0.35) | S100BCDK2CDC7ROCK2MAP4K4 | |
| SCHEMBL7800967 | 0.76 | ITK (0.38) | CDK2 | |
| SCHEMBL7809839 | 0.76 | CRHR1 (0.33) | CDK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL6573203 | 0.76 | ALDH1A1 (0.34) | S100B | |
| SCHEMBL6572636 | 0.76 | CRHR1 (0.34) | S100BMAP4K4 | |
| SCHEMBL6572502 | 0.76 | S100B (0.40) | S100BCLK4 | |
| SCHEMBL6573501 | 0.75 | S100B (0.35) | S100BCDK2CDC7ROCK2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |