Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805959 | 0.84 | KCNH2 (0.36) | ALDH1A1MAPTHPGDKMT2ANPSR1 | |
| SCHEMBL7806004 | 0.83 | LTA4H (0.38) | ALDH1A1MAPTHPGDKMT2ANPSR1 | |
| SCHEMBL7807623 | 0.79 | LTA4H (0.35) | ALDH1A1MAPTHPGDKMT2ANPSR1 | |
| SCHEMBL7461302 | 0.79 | MEN1 (0.34) | MAPTKMT2AMEN1HSD17B10KCNH2 | |
| SCHEMBL7812294 | 0.76 | — | — | |
| SCHEMBL7808839 | 0.76 | PTPN1 (0.36) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL7808604 | 0.76 | HDAC1 (0.36) | ALDH1A1MAPTHPGDKMT2ANPSR1 | |
| SCHEMBL7807633 | 0.75 | PRKCA (0.31) | CYP3A4 | |
| SCHEMBL7456352 | 0.74 | — | — | |
| SCHEMBL7456583 | 0.73 | PRKCA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |