Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.66 |
| ▸ | ITGAV | P06756 | 20/20 | 0.66 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 17/20 | 0.53 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830769 | 0.90 | ITGB3 (0.81) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL7512617 | 0.90 | ITGB3 (0.81) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL7797654 | 0.84 | ITGB3 (0.67) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL7797657 | 0.84 | ITGB3 (0.67) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6176301 | 0.80 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6177136 | 0.80 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6178494 | 0.79 | ITGB3 (0.87) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6175429 | 0.78 | ITGB3 (0.86) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL7797631 | 0.76 | THRB (0.50) | — | |
| SCHEMBL9857070 | 0.75 | SLC6A9 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |