Sulfuric Acid

Sulfuric Acid

SCHEMBL7808043

CCN(CCO)c1ccc(N)cc1N.O=S(=O)(O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.32
CHRM3 known ✓ P20309 1/20 0.32
MAOA known ✓ P21397 1/20 0.32
ALDH1A1 P00352 5/20 0.39
RECQL P46063 3/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
THRB P10828 2/20 0.39
HPGD P15428 2/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 5/20 0.39
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
MAPK1 P28482 2/20 0.36
PSMD14 O00487 1/20 0.36
GFER P55789 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PRKCI P41743 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5946493 0.92 ALDH1A1 (0.41) ALDH1A1RECQLCYP3A4TSHRCASP1
Sulfuric Acid SCHEMBL7807208 0.91 ALDH1A1 (0.43) ALDH1A1RECQLCYP3A4TSHRTHRB
Sulfuric Acid SCHEMBL8444717 0.89 GAA (0.46) ALDH1A1RECQLCYP3A4TSHRTHRB
Sulfuric Acid SCHEMBL6566761 0.87 GAA (0.38) ALDH1A1RECQLCYP3A4TSHRTHRB
SCHEMBL8626489 0.84 GAA (0.46) ALDH1A1RECQLCYP3A4TSHRTHRB
SCHEMBL8640578 0.82 CASP1 (0.35) ALDH1A1RECQLTSHRTHRBCASP1
SCHEMBL9482195 0.80 PRKCI (0.44) ALDH1A1RECQLCYP3A4TSHRALOX15
SCHEMBL8776727 0.79 ALDH1A1 (0.50) ALDH1A1RECQLCYP3A4TSHRCASP1
Sulfuric Acid SCHEMBL20570213 0.78 ALDH1A1 (0.58) ALDH1A1RECQLCYP3A4TSHRTHRB
Sulfuric Acid SCHEMBL1143794 0.78 ALDH1A1 (0.58) ALDH1A1RECQLCYP3A4TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010005914-A1 OXIDATION DYES ANDREAS J. BITTNER 2001-07-05 US disclosed
EP-0912160-A2 OXIDATION DYES Hans Schwarzkopf GmbH & Co. KG (DE) 1999-05-06 EP disclosed
WO-1998001106-A2 OXIDATION DYES HANS SCHWARZKOPF GMBH & CO. KG (DE) 1998-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010005914-A1 OXIDATION DYES AOC1, CBR3, KRT18 CHRM2 245/4885CHRM3 273/4885MAOA 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.