Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415021 | 0.79 | MAPK1 (0.48) | MAPK1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7805881 | 0.78 | ACHE (0.35) | ACHEOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7799267 | 0.75 | ACHE (0.35) | ACHEOPRM1OPRD1KCNH2 | |
| Hydrochloric Acid SCHEMBL7799266 | 0.75 | ACHE (0.35) | ACHEOPRM1OPRD1KCNH2 | |
| SCHEMBL5071115 | 0.74 | MAPK1 (0.46) | MAPK1MEN1KMT2A | |
| SCHEMBL7808250 | 0.71 | MAPK1 (0.41) | MAPK1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7804700 | 0.70 | MAPK1 (0.44) | MAPK1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL4351591 | 0.70 | MAPK1 (0.41) | MAPK1MEN1KMT2A | |
| SCHEMBL7804376 | 0.68 | MAPK1 (0.41) | MAPK1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL6018054 | 0.67 | MAPK1 (0.81) | MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |