Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076260 | 0.78 | SLC6A4 (0.41) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL23950409 | 0.73 | MAOA (0.61) | MAOAMAOBOPRM1OPRL1KDM1A | |
| SCHEMBL4591914 | 0.72 | CHRM2 (0.45) | — | |
| SCHEMBL8267929 | 0.70 | MAOA (0.68) | MAOAMAOBOPRM1OPRL1KDM1A | |
| SCHEMBL3651250 | 0.70 | MAOA (0.61) | MAOAMAOBOPRM1OPRL1KDM1A | |
| SCHEMBL1318340 | 0.69 | MAOA (1.00) | MAOAMAOBOPRM1OPRL1KDM1A | |
| SCHEMBL8267931 | 0.68 | MAOA (0.58) | MAOAMAOBHRH3 | |
| Hydrochloric Acid SCHEMBL1318464 | 0.68 | MAOA (0.95) | MAOAMAOBOPRL1KDM1A | |
| SCHEMBL7121075 | 0.67 | SLC6A3 (0.53) | MAOAMAOBOPRM1OPRL1SLC6A4 | |
| SCHEMBL1022483 | 0.67 | OPRM1 (0.54) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690055-B1 | Stereoselective process for making endo-tropanamine and like compounds | LILLY CO ELI (US) | 2001-11-14 | — | — | EP | disclosed |
| US-5625065-A | Stereoselective process for making endo-tropanamine and like compounds | ELI LILLY AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0690055-A1 | Stereoselective process for making endo-tropanamine and like compounds | ELI LILLY AND COMPANY (US) | 1996-01-03 | — | — | EP | disclosed |