Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7946657 | 0.99 | NOTUM (0.36) | NOTUMHTR4PDE4AGPR55CNR1 | |
| SCHEMBL7808385 | 0.94 | HTR3A (0.34) | GPR55 | |
| Hydrochloric Acid SCHEMBL7945320 | 0.93 | HTR3A (0.34) | GPR55 | |
| SCHEMBL8304451 | 0.86 | NOTUM (0.38) | NOTUMHTR4PDE4AGPR55CNR1 | |
| Hydrochloric Acid SCHEMBL8366408 | 0.85 | NOTUM (0.37) | NOTUMHTR4PDE4AGPR55CNR1 | |
| SCHEMBL7804900 | 0.81 | BRD4 (0.33) | NOTUMPDE4A | |
| SCHEMBL8305677 | 0.81 | HTR4 (0.43) | NOTUMHTR4PDE4AGPR55CNR1 | |
| Hydrochloric Acid SCHEMBL7946906 | 0.80 | DRD2 (0.33) | NOTUMPDE4A | |
| Hydrochloric Acid SCHEMBL8366413 | 0.80 | HTR4 (0.43) | NOTUMHTR4PDE4AGPR55CNR1 | |
| SCHEMBL8304573 | 0.80 | HTR3A (0.35) | GPR55CNR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975631-B1 | 5-ARYL-3-(8-AZABICYCLO[3.2.1]OCT-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AS 5-HT4 RECEPTOR LIGANDS | SANOFI SYNTHELABO (FR) | 2001-10-04 | — | — | EP | disclosed |