Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812179 | 0.82 | LTA4H (0.38) | KCNH2MAPTALDH1A1GAAKDM4E | |
| SCHEMBL7812159 | 0.81 | KCNH2 (0.40) | KCNH2MAPTALDH1A1GAAKDM4E | |
| SCHEMBL18421930 | 0.72 | KDM4E (0.31) | MAPTALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL6572205 | 0.72 | — | — | |
| SCHEMBL6572958 | 0.71 | PLA2G7 (0.45) | MAPTALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL6574499 | 0.70 | ALDH1A1 (0.39) | KCNH2MAPTALDH1A1GAAKDM4E | |
| SCHEMBL6870781 | 0.70 | KCNH2 (0.48) | KCNH2MAPTALDH1A1GAAKDM4E | |
| SCHEMBL33847 | 0.70 | KCNH2 (0.53) | KCNH2MAPTALDH1A1GAAKDM4E | |
| SCHEMBL7809761 | 0.69 | NPC1 (0.40) | KCNH2MAPTALDH1A1GAAKDM4E | |
| SCHEMBL16600073 | 0.68 | KCNH2 (0.55) | KCNH2MAPTALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |