Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604567 | 0.85 | SLC6A4 (0.58) | SLC6A4KMT2AHRH1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7806943 | 0.84 | LMNA (0.59) | SLC6A4KMT2AHRH1LMNAMAPT | |
| SCHEMBL7810899 | 0.81 | KMT2A (0.53) | SLC6A4KMT2AHRH1LMNAMAPT | |
| SCHEMBL4678769 | 0.80 | SLC6A4 (0.63) | SLC6A4KMT2AHRH1LMNAMAPT | |
| Imipramine SCHEMBL2822809 | 0.77 | SLC6A4 (0.59) | SLC6A4KMT2AHRH1LMNAMAPT | |
| SCHEMBL7808399 | 0.76 | MAPK1 (0.51) | SLC6A4KMT2AHRH1LMNAMAPT | |
| SCHEMBL218473 | 0.72 | SLC6A4 (0.66) | SLC6A4KMT2AHRH1LMNAMAPT | |
| SCHEMBL4733904 | 0.72 | SLC6A4 (0.65) | SLC6A4KMT2AHRH1LMNAMAPT | |
| SCHEMBL4907497 | 0.72 | TSHR (0.65) | SLC6A4KMT2ALMNAMAPTSLC6A2 | |
| Imipramine SCHEMBL20644144 | 0.71 | SLC6A4 (0.83) | SLC6A4KMT2AHRH1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820443-B1 | HETEROCYCLIC COMPOUNDS FOR TREATING DIABETES | NOVO NORDISK AS (DK) | 2001-09-19 | — | — | EP | disclosed |
| EP-0820443-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996031481-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |