Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 9/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8031534 | 0.99 | HTR2C (0.58) | HTR2CHTR2AHTR6BCHEHTR1D | |
| SCHEMBL847974 | 0.75 | HTR2C (0.68) | HTR2CHTR2AHTR6HTR1DCNR2 | |
| SCHEMBL337413 | 0.75 | HTR2C (0.68) | HTR2CHTR2AHTR6HTR1DCNR2 | |
| SCHEMBL23956102 | 0.75 | HTR2C (0.68) | HTR2CHTR2AHTR6HTR1DCNR2 | |
| SCHEMBL23927902 | 0.72 | HTR2C (0.64) | HTR2CHTR2AHTR6HTR1D | |
| SCHEMBL4329685 | 0.71 | HTR2C (0.62) | HTR2CHTR2AHTR6HTR1DKDM1A | |
| SCHEMBL15999003 | 0.70 | HTR2C (0.65) | HTR2CHTR2AHTR6HTR1DCNR2 | |
| SCHEMBL7804094 | 0.70 | HTR6 (0.49) | HTR6BCHEHTR1D | |
| Hydrochloric Acid SCHEMBL8031680 | 0.70 | HTR6 (0.48) | HTR6BCHEHTR1D | |
| SCHEMBL7798188 | 0.69 | HTR2C (0.54) | HTR2CHTR2AHTR6HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |