SCHEMBL7808764

SCHEMBL7808764

c1cc(-n2cnnc2)c2ccn(CC3CCNC3)c2c1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 17/20 0.46
HTR6 P50406 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8021832 0.99 KDM1A (0.45) KDM1AHTR6
SCHEMBL8174767 0.75 KDM1A (0.44) KDM1A
SCHEMBL7806983 0.74 KDM1A (0.44) KDM1A
Hydrochloric Acid SCHEMBL7806965 0.74 KDM1A (0.44) KDM1A
Hydrochloric Acid SCHEMBL8035094 0.73 KDM1A (0.43) KDM1A
SCHEMBL26360136 0.70 DRD2 (0.40) KDM1AHTR6
SCHEMBL26113319 0.70 TUBB4A (0.39) KDM1AHTR6
SCHEMBL26113308 0.68 DDB1 (0.41) KDM1AHTR6
SCHEMBL7808693 0.67 HTR2C (0.59) KDM1AHTR6
SCHEMBL7798285 0.67 SLC6A2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0902027-B1 Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them ADIR (FR) 2001-07-25 EP disclosed
EP-0902027-A1 Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1999-03-17 EP disclosed