Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808045 | 0.88 | GAA (0.47) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL7813210 | 0.85 | GAA (0.49) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL7808110 | 0.84 | GAA (0.48) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL8380205 | 0.83 | GAA (0.51) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL8535695 | 0.83 | GAA (0.51) | GAAMAPTTP53GLAKDM4E | |
| SCHEMBL1012916 | 0.82 | GAA (0.48) | GAAMAPTTP53GLASMN1; SMN2 | |
| SCHEMBL7808085 | 0.82 | GAA (0.50) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL10950577 | 0.81 | ALDH1A1 (0.52) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL7801293 | 0.81 | PTK2 (0.48) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL116126 | 0.80 | CDK1 (0.55) | GAAMAPTTP53GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971902-B1 | AMINOSULFONYLUREAS WITH HERBICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2001-12-19 | — | — | EP | disclosed |
| US-6329323-B1 | AMINOTRIAZINE DERIVATIVES | ISAGRO RICERCA S.R.L. (IT) | 2001-12-11 | — | — | US | disclosed |