SCHEMBL7809532

SCHEMBL7809532

COS(=O)(=O)Oc1c(C(C)=O)c(=O)[nH]c2c(-c3ccccc3)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 1/20 0.40
KDM4E B2RXH2 3/20 0.39
SERPINE1 P05121 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HK2 P52789 1/20 0.37
ALDH1A1 P00352 2/20 0.34
TUBB4A P04350 2/20 0.34
TUBB P07437 2/20 0.34
TUBA3C P0DPH7 2/20 0.34
TUBA1B P68363 2/20 0.34
TUBA4A P68366 2/20 0.34
TUBB4B P68371 2/20 0.34
TUBB3 Q13509 2/20 0.34
TUBB2A Q13885 2/20 0.34
TUBB8 Q3ZCM7 2/20 0.34
TUBA3E Q6PEY2 2/20 0.34
TUBA1A Q71U36 2/20 0.34
TUBA1C Q9BQE3 2/20 0.34
TUBB6 Q9BUF5 2/20 0.34
TUBB2B Q9BVA1 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809496 0.84 KDM4E (0.43) KDM4EALDH1A1LMNAGAATSHR
SCHEMBL7813787 0.83 TUBB4A (0.39) FEN1KDM4EALDH1A1TUBB4ATUBB
SCHEMBL7804023 0.83 TUBB4A (0.39) KDM4EALDH1A1TUBB4ATUBBTUBA3C
SCHEMBL7809663 0.82 DAO (0.38) KDM4EALDH1A1LMNATSHRHSD17B10
SCHEMBL7803962 0.81 DAO (0.37) KDM4EALDH1A1
SCHEMBL7817118 0.81 CAPN1 (0.42) KDM4ESMN1; SMN2ALDH1A1LMNAHSD17B10
SCHEMBL7809535 0.81 FEN1 (0.42) FEN1KDM4ESERPINE1SMN1; SMN2HK2
SCHEMBL7809476 0.80 PLA2G7 (0.34) KDM4EALDH1A1LMNAGLAGAA
SCHEMBL7811360 0.72 TUBB4A (0.37) FEN1KDM4ESMN1; SMN2ALDH1A1TUBB4A
SCHEMBL7811062 0.71 KDM4E (0.35) KDM4EALDH1A1GAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533882-B1 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM KOREA RES INST CHEM TECH (KR) 2001-02-07 EP disclosed
US-5430153-A Insecticides, fungicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-07-04 US disclosed