Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27551847 | 0.86 | CA1 (0.36) | ALDH1A1KDM4ETDP1CA2CA1 | |
| SCHEMBL8472881 | 0.81 | CA9 (0.42) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7809603 | 0.81 | CA1 (0.45) | ALDH1A1KDM4ECA2CA1CA12 | |
| SCHEMBL9661196 | 0.79 | TSHR (0.40) | ALDH1A1TDP1NPC1RAB9ACA2 | |
| SCHEMBL9661211 | 0.79 | ALOX5 (0.37) | ABCB11ALOX5ALOX5APFEN1SLCO1B1 | |
| SCHEMBL8477927 | 0.78 | RAB9A (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL27478868 | 0.78 | GABRA1 (0.33) | CA2CA1MAPTCA12CA9 | |
| SCHEMBL11965637 | 0.73 | MAPK1 (0.40) | MAPK1ALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL9659132 | 0.73 | MEN1 (0.34) | SMN1; SMN2CA2CA1CA12CA9 | |
| SCHEMBL2015049 | 0.71 | MAPK1 (0.45) | MAPK1ALDH1A1KDM4ETDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245058-B1 | HERBICIDAL HETEROCYCLIC SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5011527-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4906278-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4778512-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0245058-A2 | Herbicidal heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-11 | — | — | EP | disclosed |