Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484192 | 0.78 | CA12 (0.56) | IMPDH2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1895643 | 0.76 | CYP2C9 (0.57) | ALDH1A1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5735824 | 0.76 | MKNK1 (0.59) | ALDH1A1KMT2AHSD17B10L3MBTL1MMP2 | |
| SCHEMBL6755274 | 0.76 | ALDH1A1 (0.67) | IMPDH2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL31189439 | 0.76 | MMP2 (0.50) | IMPDH2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10028690 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHPGDTP53 | |
| SCHEMBL27650006 | 0.75 | HSD17B10 (0.66) | IMPDH2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL30590650 | 0.75 | MMP2 (0.49) | IMPDH2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5487018 | 0.75 | CYP11B2 (0.74) | ALDH1A1MEN1KMT2AHPGDMMP2 | |
| SCHEMBL29363035 | 0.74 | KDM4E (0.56) | ALDH1A1MEN1KMT2AHPGDMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |