Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035940 | 0.80 | CYP11B1 (0.49) | KMT2AL3MBTL1ALDH1A1KDM4ETDP1 | |
| SCHEMBL11068897 | 0.77 | TBXAS1 (0.62) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10984891 | 0.77 | MAPT (0.44) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL1779695 | 0.76 | RAB9A (0.68) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7811371 | 0.75 | ALDH1A1 (0.51) | KMT2AL3MBTL1ALDH1A1NTRK1 | |
| SCHEMBL20037234 | 0.75 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27848412 | 0.74 | TDP1 (0.53) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25143868 | 0.74 | L3MBTL1 (0.71) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11181973 | 0.74 | ALDH1A1 (0.57) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL18202169 | 0.73 | MEN1 (0.74) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |