Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814073 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2GRM3HPGDALDH1A1KDM4E | |
| SCHEMBL7813630 | 0.88 | ALDH1A1 (0.51) | SMN1; SMN2CYP3A4ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL7814388 | 0.88 | ALDH1A1 (0.54) | SMN1; SMN2POLBGRM3HPGDUSP2 | |
| SCHEMBL7817546 | 0.88 | PPARD (0.49) | SMN1; SMN2HPGDCYP3A4KDM4ETSHR | |
| SCHEMBL7811927 | 0.84 | PARP10 (0.53) | SMN1; SMN2HPGDUSP2ALDH1A1KDM4E | |
| SCHEMBL8161638 | 0.83 | USP2 (0.67) | SMN1; SMN2POLBGRM3HPGDUSP2 | |
| SCHEMBL7814142 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP3A4ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL7814122 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP3A4ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL7814125 | 0.81 | ALDH1A1 (0.72) | SMN1; SMN2HPGDUSP2CYP3A4ALDH1A1 | |
| SCHEMBL3642036 | 0.81 | GRM3 (0.71) | SMN1; SMN2POLBGRM3USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |