Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814073 | 0.88 | SMN1; SMN2 (0.49) | ALDH1A1LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL7809970 | 0.88 | SMN1; SMN2 (0.60) | ALDH1A1CYP3A4CYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL7817546 | 0.88 | PPARD (0.49) | CYP3A4SMN1; SMN2TSHRCA12CA1 | |
| SCHEMBL7817767 | 0.87 | LMNA (0.55) | ALDH1A1LMNACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7814142 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1LMNACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7811927 | 0.82 | PARP10 (0.53) | ALDH1A1LMNASMN1; SMN2TSHRCA12 | |
| SCHEMBL7814122 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1LMNACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7810083 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7814130 | 0.79 | LMNA (0.54) | ALDH1A1LMNACYP2C9TSHRCA12 | |
| SCHEMBL7813550 | 0.79 | CYP1A2 (0.51) | ALDH1A1CYP3A4CYP2D6CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |