Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813630 | 0.88 | ALDH1A1 (0.51) | TSHRSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL7814073 | 0.88 | SMN1; SMN2 (0.49) | PPARAHPGDSMN1; SMN2CA12CA1 | |
| SCHEMBL7809970 | 0.88 | SMN1; SMN2 (0.60) | MEN1HPGDTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7813918 | 0.88 | PKLR (0.51) | PPARDPPARAMEN1HPGDTSHR | |
| SCHEMBL7817538 | 0.82 | PPARD (0.68) | PPARDPPARAMEN1HPGDTSHR | |
| SCHEMBL7811927 | 0.82 | PARP10 (0.53) | PPARAHPGDTSHRSMN1; SMN2CA12 | |
| SCHEMBL7814142 | 0.80 | SMN1; SMN2 (0.47) | PPARAMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7810110 | 0.80 | HSD11B1 (0.51) | PPARDPPARAMEN1HPGDTSHR | |
| SCHEMBL7814122 | 0.80 | SMN1; SMN2 (0.46) | PPARAMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL29844006 | 0.79 | MEN1 (0.55) | MEN1HPGDTSHRKMT2AGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |