Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811598 | 0.89 | LMNA (0.46) | SMN1; SMN2KDM4EPARP10PARP14CA12 | |
| SCHEMBL7814122 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EPARP10PARP14CA12 | |
| SCHEMBL7809970 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL7813630 | 0.83 | ALDH1A1 (0.51) | SMN1; SMN2KDM4ECA12CA1CA2 | |
| SCHEMBL7814073 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EPARP10PARP14CA12 | |
| SCHEMBL7817568 | 0.82 | ITGB3 (0.58) | SMN1; SMN2KDM4EITGB3ITGA2BLMNA | |
| SCHEMBL7811927 | 0.82 | PARP10 (0.53) | SMN1; SMN2KDM4EPARP10PARP14CA12 | |
| SCHEMBL7817546 | 0.80 | PPARD (0.49) | SMN1; SMN2KDM4EPARP10PARP14CA12 | |
| SCHEMBL7817531 | 0.80 | HSD11B1 (0.46) | PARP10PARP14CA12CA1CA2 | |
| SCHEMBL7813532 | 0.78 | LMNA (0.42) | SMN1; SMN2KDM4EPARP10PARP14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |