Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011061 | 0.82 | CCR5 (0.54) | CYP2C9CCR5GAAALDH1A1HTT | |
| SCHEMBL7813405 | 0.82 | ALDH1A1 (0.72) | CYP2C9CYP3A4CYP2C19ITGB3ITGA2B | |
| SCHEMBL7814105 | 0.82 | BCL9 (0.54) | CYP2C9CCR5GAAALDH1A1HTT | |
| SCHEMBL7817601 | 0.81 | NPC1 (0.54) | PARP14PARP10HRH1CCR3NPC1 | |
| SCHEMBL27299337 | 0.81 | CCR5 (0.68) | CCR5GAAALDH1A1HTTHPGDS | |
| SCHEMBL7810116 | 0.79 | LMNA (0.63) | CYP2C9CYP3A4CYP2C19ITGB3ITGA2B | |
| SCHEMBL7813988 | 0.78 | L3MBTL1 (0.58) | CCR5GAAALDH1A1EGLN1NPC1 | |
| SCHEMBL7811526 | 0.78 | PARP10 (0.53) | CCR5ALDH1A1KDM4EPARP14PARP10 | |
| SCHEMBL7811507 | 0.77 | CCR3 (0.47) | CYP2C9PARP14PARP10CCR3NPC1 | |
| SCHEMBL7814284 | 0.77 | ALDH1A1 (0.57) | CCR5ALDH1A1HTTPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |