Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17609265 | 0.80 | FGFR1 (0.37) | LMNANPC1RAB9APKMFGFR1 | |
| SCHEMBL10889581 | 0.76 | TDP1 (0.52) | LMNAFGFR1SMN1; SMN2KMT2AHTT | |
| SCHEMBL20422010 | 0.76 | ALOX5 (0.56) | LMNAPKMFGFR1SMN1; SMN2KMT2A | |
| SCHEMBL537903 | 0.73 | HSD17B10 (0.53) | LMNANPC1RAB9APKMFGFR1 | |
| SCHEMBL9696692 | 0.73 | HSD17B10 (0.53) | LMNANPC1RAB9APKMFGFR1 | |
| SCHEMBL3553238 | 0.73 | HSD17B10 (0.53) | LMNANPC1RAB9APKMFGFR1 | |
| SCHEMBL8906261 | 0.72 | RAB9A (0.47) | LMNANPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL31069753 | 0.69 | ALDH3A1 (0.46) | NPC1RAB9AFGFR1SMN1; SMN2KMT2A | |
| SCHEMBL7948888 | 0.69 | TDP1 (0.56) | LMNANPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL7804822 | 0.69 | TDP1 (0.52) | LMNAFGFR1SMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830345-B1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 2001-09-05 | — | — | EP | claimed |