Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811522 | 0.92 | ACHE (0.50) | KMT2AL3MBTL3L3MBTL1HTTHPGD | |
| SCHEMBL7811611 | 0.85 | NPC1 (0.56) | KMT2AL3MBTL3L3MBTL1HTTHPGD | |
| SCHEMBL7810081 | 0.79 | KMT2A (0.49) | KMT2AHPGDPOLBSLC6A4HRH3 | |
| SCHEMBL7817608 | 0.78 | ALDH1A1 (0.50) | KMT2AHTTLMNATP53POLB | |
| SCHEMBL7811667 | 0.77 | KMT2A (0.47) | KMT2AL3MBTL3L3MBTL1HTTHPGD | |
| SCHEMBL7811441 | 0.76 | MME (0.46) | KMT2AHPGDPOLBSLC6A4HRH3 | |
| SCHEMBL7817804 | 0.75 | NPC1 (0.54) | L3MBTL3L3MBTL1HTTHPGDMGLL | |
| SCHEMBL7814002 | 0.73 | KMT2A (0.40) | KMT2AHPGDPOLBSLC6A4HRH3 | |
| SCHEMBL14600382 | 0.69 | HTT (0.66) | KMT2AHTTHPGDMGLLHSD11B1 | |
| SCHEMBL7817391 | 0.69 | MAOB (0.54) | KMT2AHPGDLMNAPOLBSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |