Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820098 | 0.90 | CYP1A2 (0.40) | L3MBTL1MBTPS1MAPTHSP90AA1CYP1A2 | |
| SCHEMBL7812791 | 0.82 | CACNA1B (0.45) | LMNAL3MBTL1CACNA1BMMP13GABRA1 | |
| SCHEMBL7822124 | 0.74 | JMJD6 (0.36) | LMNAMBTPS1MAPTMEN1KMT2A | |
| SCHEMBL7820096 | 0.73 | CYP1A2 (0.39) | CACNA1BMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL7825521 | 0.72 | ALDH1A1 (0.38) | LMNAL3MBTL1CACNA1BMBTPS1MAPT | |
| SCHEMBL7470311 | 0.70 | MBTPS1 (0.33) | LMNAMBTPS1CYP1A2NPC1RAB9A | |
| SCHEMBL7456343 | 0.67 | CA12 (0.43) | LMNAMBTPS1MAPTMEN1KMT2A | |
| SCHEMBL9367416 | 0.66 | LMNA (1.00) | LMNAL3MBTL1MAPTMAOB | |
| SCHEMBL9621415 | 0.66 | LMNA (1.00) | LMNAL3MBTL1MAPTMAOB | |
| SCHEMBL9469655 | 0.66 | LMNA (1.00) | LMNAL3MBTL1MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065895-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 1999-12-23 | — | — | WO | disclosed |