Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | MBTPS1 | Q14703 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812795 | 0.90 | LMNA (0.46) | CYP1A2MAPTMBTPS1NPC1RAB9A | |
| SCHEMBL7822124 | 0.82 | JMJD6 (0.36) | MAPTSLC6A2SLC6A4SLC6A3MBTPS1 | |
| SCHEMBL7820096 | 0.78 | CYP1A2 (0.39) | CYP1A2MAPTHTR2ARAB9ASMN1; SMN2 | |
| SCHEMBL7825521 | 0.77 | ALDH1A1 (0.38) | MAPTSLC6A2SLC6A4SLC6A3MBTPS1 | |
| SCHEMBL7456343 | 0.74 | CA12 (0.43) | MAPTSLC6A2SLC6A4SLC6A3MBTPS1 | |
| SCHEMBL7470311 | 0.72 | MBTPS1 (0.33) | CYP1A2SLC6A2SLC6A4SLC6A3MBTPS1 | |
| SCHEMBL7812791 | 0.71 | CACNA1B (0.45) | CYP1A2MAPTMBTPS1RAB9AKDM4E | |
| SCHEMBL7813717 | 0.70 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7459899 | 0.69 | MAPT (0.37) | MAPTSLC6A2SLC6A4MBTPS1RAB9A | |
| SCHEMBL28801510 | 0.67 | CYP1A2 (0.59) | CYP1A2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065895-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 1999-12-23 | — | — | WO | disclosed |