Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812791 | 0.92 | CACNA1B (0.45) | CYP1A2MAPTSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7822122 | 0.83 | MAPT (0.36) | MAPTALDH1A1SMN1; SMN2GALR3TSHR | |
| SCHEMBL7825517 | 0.79 | PRMT5 (0.40) | ALDH1A1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL7820098 | 0.78 | CYP1A2 (0.40) | CYP1A2MAPTSMN1; SMN2RAB9AHTR2A | |
| SCHEMBL7456333 | 0.74 | SLC6A2 (0.43) | MAPTALDH1A1TSHRHTR2AMEN1 | |
| SCHEMBL7470305 | 0.73 | MAPT (0.37) | MAPTALDH1A1SMN1; SMN2GALR3TSHR | |
| SCHEMBL7812795 | 0.73 | LMNA (0.46) | CYP1A2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL7813715 | 0.72 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL7473197 | 0.70 | HRH3 (0.33) | MAPTALDH1A1 | |
| SCHEMBL7073107 | 0.69 | ADRB3 (0.51) | MAPTALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065895-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 1999-12-23 | — | — | WO | disclosed |