⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423619 | 0.77 | — | — | |
| SCHEMBL7805842 | 0.74 | — | — | |
| SCHEMBL7813388 | 0.73 | — | — | |
| SCHEMBL7805839 | 0.73 | RARB (0.32) | — | |
| SCHEMBL7812219 | 0.72 | RXRA (0.43) | — | |
| SCHEMBL8423718 | 0.69 | CYP3A4 (0.38) | — | |
| SCHEMBL8424636 | 0.69 | RXRA (0.48) | — | |
| SCHEMBL7812403 | 0.69 | RXRA (0.35) | — | |
| SCHEMBL7806225 | 0.68 | RARA (0.34) | — | |
| SCHEMBL7813043 | 0.68 | RARA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816352-B1 | Bi-aryl heterocyclic compounds and their use in human or veterinary medicine and in cosmetics | CT INTERNAT DE (FR) | 2001-02-21 | — | — | EP | claimed |
| US-5905088-A | SKIN DISORDERS, RHEUMATIC DISEASES, RESPIRATORY SYSTEM OR CARDIOVASCULAR DISORDERS AND OPTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-05-18 | — | — | US | claimed |
| EP-0816352-A1 | Bi-aryl heterocyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-01-07 | — | — | EP | claimed |
| EP-0816352-B1 | Bi-aryl heterocyclic compounds and their use in human or veterinary medicine and in cosmetics | CT INTERNAT DE (FR) | 2001-02-21 | — | — | EP | disclosed |
| US-5905088-A | SKIN DISORDERS, RHEUMATIC DISEASES, RESPIRATORY SYSTEM OR CARDIOVASCULAR DISORDERS AND OPTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-05-18 | — | — | US | disclosed |
| EP-0816352-A1 | Bi-aryl heterocyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-01-07 | — | — | EP | disclosed |