Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.48 |
| ▸ | RXRB | P28702 | 8/20 | 0.48 |
| ▸ | RXRG | P48443 | 8/20 | 0.48 |
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | RARG | P13631 | 6/20 | 0.44 |
| ▸ | RARA | P10276 | 4/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812840 | 0.82 | RXRA (0.34) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7813388 | 0.80 | — | — | |
| SCHEMBL7816655 | 0.79 | RARA (0.35) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7812219 | 0.78 | RXRA (0.43) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7808934 | 0.76 | RXRA (0.58) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7813043 | 0.74 | RARA (0.34) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7806225 | 0.74 | RARA (0.34) | RXRARXRGRARBRARGRARA | |
| SCHEMBL8423718 | 0.73 | CYP3A4 (0.38) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7812403 | 0.72 | RXRA (0.35) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7810811 | 0.71 | CYP26A1 (0.43) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905088-A | SKIN DISORDERS, RHEUMATIC DISEASES, RESPIRATORY SYSTEM OR CARDIOVASCULAR DISORDERS AND OPTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-05-18 | — | — | US | claimed |
| US-5905088-A | SKIN DISORDERS, RHEUMATIC DISEASES, RESPIRATORY SYSTEM OR CARDIOVASCULAR DISORDERS AND OPTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-05-18 | — | — | US | disclosed |