Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336059 | 0.94 | ALOX15 (0.61) | ALOX15SMN1; SMN2ALDH1A1TSHRRXRA | |
| Formaldehyde SCHEMBL28598974 | 0.91 | ALOX15 (0.57) | ALOX15SMN1; SMN2ALDH1A1TSHRRXRA | |
| SCHEMBL23512464 | 0.89 | ALOX15 (0.55) | ALOX15SMN1; SMN2ALDH1A1TSHRRXRA | |
| SCHEMBL11552274 | 0.87 | ALOX15 (0.71) | ALOX15SMN1; SMN2ALDH1A1TSHRFFAR1 | |
| SCHEMBL22065481 | 0.81 | ALOX15 (0.63) | ALOX15SMN1; SMN2ALDH1A1TSHRFFAR1 | |
| SCHEMBL5009454 | 0.81 | ALOX15 (0.83) | ALOX15SMN1; SMN2ALDH1A1RAB9AFFAR1 | |
| SCHEMBL339492 | 0.80 | ALOX15 (0.81) | ALOX15SMN1; SMN2ALDH1A1TSHRFFAR1 | |
| SCHEMBL12612087 | 0.80 | LMNA (0.60) | ALOX15SMN1; SMN2ALDH1A1TSHRFFAR1 | |
| SCHEMBL11530406 | 0.79 | RAB9A (0.56) | SMN1; SMN2ALDH1A1RXRARXRBKDM4E | |
| Diphenylether SCHEMBL27914216 | 0.79 | ALOX15 (0.87) | ALOX15SMN1; SMN2ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1314906-A | Salts of paroxetine | SMITHKLINE BEECHAM PLC (GB) | 2001-09-26 | — | — | CN | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |