Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336059 | 0.94 | ALOX15 (0.61) | ALOX15SMN1; SMN2ALDH1A1TSHRRXRA | |
| Formaldehyde SCHEMBL28598974 | 0.91 | ALOX15 (0.57) | ALOX15SMN1; SMN2ALDH1A1TSHRRXRA | |
| SCHEMBL7813264 | 0.89 | ALOX15 (0.55) | ALOX15SMN1; SMN2ALDH1A1TSHRRXRA | |
| SCHEMBL2780802 | 0.87 | ALOX15 (0.71) | ALOX15SMN1; SMN2ALDH1A1TSHRPPARD | |
| SCHEMBL22144522 | 0.85 | RARB (0.54) | SMN1; SMN2ALDH1A1RXRARXRBPPARD | |
| SCHEMBL12646485 | 0.84 | ALOX15 (0.57) | ALOX15SMN1; SMN2ALDH1A1PPARDPPARG | |
| SCHEMBL421532 | 0.81 | L3MBTL1 (0.59) | ALOX15SMN1; SMN2ALDH1A1TSHRFFAR1 | |
| SCHEMBL25146826 | 0.81 | ALDH1A1 (0.54) | ALOX15SMN1; SMN2ALDH1A1TSHRPPARD | |
| SCHEMBL9653716 | 0.81 | PPARA (0.64) | ALDH1A1TSHRPPARGLTB4R2PPARA | |
| SCHEMBL422442 | 0.81 | ALOX15 (0.76) | ALOX15SMN1; SMN2ALDH1A1PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |