Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688338 | 0.89 | KMT2A (0.63) | KMT2AALOX5PTGESESR1KEAP1 | |
| SCHEMBL7825360 | 0.77 | KEAP1 (0.55) | ATMKMT2AALOX5PTGESKEAP1 | |
| SCHEMBL7826084 | 0.77 | ALDH1A1 (0.64) | KMT2AALOX5PTGESTAS2R14KEAP1 | |
| SCHEMBL7814298 | 0.74 | KEAP1 (0.52) | KMT2AALOX5PTGESTAS2R14KEAP1 | |
| SCHEMBL6831270 | 0.73 | PSEN1 (0.66) | KMT2AKEAP1NFE2L2C5AR1LMNA | |
| Toluene SCHEMBL18406233 | 0.72 | ALDH1A1 (0.73) | ALDH1A1TP53MAPT | |
| 4-Methylbenzoic Acid SCHEMBL29038296 | 0.72 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1MAPT | |
| Benzoic Acid SCHEMBL18406236 | 0.72 | ALDH1A1 (0.67) | KMT2ALMNAMEN1ALDH1A1MAPT | |
| 4-Methylbenzoic Acid SCHEMBL11383447 | 0.72 | ALDH1A1 (0.79) | ATMKMT2AALOX5LMNAMEN1 | |
| 4-Methylbenzoic Acid SCHEMBL11280739 | 0.72 | ALDH1A1 (0.79) | ATMKMT2AALOX5LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |