Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817501 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AKDM4EITGB3 | |
| SCHEMBL7813512 | 0.89 | MAPT (0.55) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL7804363 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL29748794 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL7813414 | 0.85 | ITGB3 (0.50) | ALDH1A1MEN1KMT2AKDM4EITGB3 | |
| SCHEMBL7814235 | 0.83 | LMNA (0.71) | ALDH1A1MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL27295608 | 0.83 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL9011213 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AKDM4EITGB3 | |
| SCHEMBL7811681 | 0.82 | CCR5 (0.52) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL7811597 | 0.81 | AVPR1A (0.54) | ALDH1A1MEN1KMT2AKDM4EITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |