Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176371 | 0.85 | TAAR1 (0.52) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL14032253 | 0.85 | TAAR1 (0.52) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL24897744 | 0.85 | ALDH1A1 (0.48) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL14542152 | 0.84 | CPA1 (0.60) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL750878 | 0.84 | CPA1 (0.60) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL16488807 | 0.84 | CPA1 (0.60) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL3512373 | 0.83 | MEN1 (0.51) | KMT2AMEN1ACACBPPARGPPARA | |
| SCHEMBL15134800 | 0.83 | NPC1 (0.46) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL21427056 | 0.83 | EPHX1 (0.43) | ACACBPPARGPPARAHPGDALOX5 | |
| SCHEMBL763623 | 0.83 | MME (0.49) | KMT2AMEN1ITGB3ITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702427-B2 | Substituted 2-pyridone tricyclic compounds, analogues thereof, and methods using same | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-07-18 | — | — | US | disclosed |
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-9138493-B2 | Radioiodinated fatty acids | GE HEALTHCARE LIMITED (GB) | 2015-09-22 | — | — | US | disclosed |
| US-20130272960-A1 | RADIOIODINATED FATTY ACIDS | GE HEALTHCARE LIMITED (GB) | 2013-10-17 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130272960-A1 | RADIOIODINATED FATTY ACIDS | FFAR3, FFAR1, FFAR2 | KMT2A 3313/4885MEN1 1752/4885FFAR1 2/4885 |
| US-11702427-B2 | Substituted 2-pyridone tricyclic compounds, analogues thereof, and methods using same | HAVCR2, HPD, CYP24A1 | KMT2A 1259/4885MEN1 1785/4885FFAR1 3709/4885 |
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SSB, UACA, CDA | KMT2A 199/4885MEN1 515/4885FFAR1 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.