Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843567 | 0.98 | ALDH1A1 (0.43) | ALDH1A1TDP1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL7823338 | 0.97 | NOTUM (0.40) | ALDH1A1TDP1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL3573592 | 0.88 | NOTUM (0.38) | ALDH1A1TDP1NOTUMQPCTKMT2A | |
| SCHEMBL2724582 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TDP1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL3260136 | 0.86 | SIGMAR1 (0.42) | ALDH1A1NOTUMQPCTKMT2ASMN1; SMN2 | |
| SCHEMBL3578214 | 0.86 | MAPK1 (0.40) | ALDH1A1L3MBTL1NOTUMQPCTKMT2A | |
| SCHEMBL3575078 | 0.84 | NOTUM (0.35) | NOTUMQPCTRAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL2945346 | 0.80 | GRM5 (0.32) | ALDH1A1TDP1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL2725130 | 0.79 | GRM5 (0.34) | ALDH1A1TDP1NOTUMQPCTKMT2A | |
| SCHEMBL3572019 | 0.79 | IDH1 (0.32) | NOTUMQPCTIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788498-B1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-08-16 | — | — | EP | disclosed |
| CN-1068325-C | phenyl oxazolidinone antibacterial agents | PHARMACIA & UPJOHN CO LLC (US) | 2001-07-11 | — | — | CN | disclosed |
| US-5883093-A | TREATING MICROBIAL INFECTIONS IN WARM BLOODED ANIMALS, INCLUDING HUMANS | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| CN-1162312-A | Phenyloxazolidinone antimicrobials | PHARMACIA & UPJOHN CO LLC (US) | 1997-10-15 | — | — | CN | disclosed |
| EP-0788498-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013502-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |