Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.31 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3014039 | 0.93 | NOTUM (0.33) | GRM5USP30NOTUMALDH1A1QPCT | |
| SCHEMBL7823338 | 0.80 | NOTUM (0.40) | GRM5NOTUML3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL7814733 | 0.80 | ALDH1A1 (0.41) | GRM5NOTUML3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL1843567 | 0.79 | ALDH1A1 (0.43) | GRM5NOTUML3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL6760968 | 0.78 | NOTUM (0.34) | GRM5NOTUM | |
| SCHEMBL2724582 | 0.73 | ALDH1A1 (0.38) | GRM5NOTUML3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL3573592 | 0.72 | NOTUM (0.38) | GRM5NOTUMALDH1A1TDP1QPCT | |
| SCHEMBL3586944 | 0.72 | ALDH1A1 (0.33) | NOTUMALDH1A1QPCT | |
| SCHEMBL28296440 | 0.72 | NOTUM (0.33) | NOTUMQPCT | |
| SCHEMBL3260136 | 0.71 | SIGMAR1 (0.42) | NOTUMALDH1A1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141161-A1 | 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | disclosed |