Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823020 | 0.88 | HSD17B3 (0.34) | HSD17B3MAPTTSHRMAPK1HTT | |
| SCHEMBL7814954 | 0.86 | ALDH1A1 (0.43) | MAPTTSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7826746 | 0.83 | MAPT (0.33) | HSD17B3MAPTTSHRMAPK1HTT | |
| SCHEMBL7829873 | 0.82 | HSD17B3 (0.38) | HSD17B3MAPTTSHRMAPK1HTT | |
| SCHEMBL7822244 | 0.82 | MCL1 (0.32) | MAPTTSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7483011 | 0.81 | MAOA (0.43) | MAPTTSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7822820 | 0.76 | ALDH1A1 (0.42) | MAPTTSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7481269 | 0.76 | HSD17B3 (0.34) | HSD17B3MAPTTSHRMAPK1HTT | |
| SCHEMBL7822480 | 0.74 | TSHR (0.34) | MAPTTSHRMAPK1HTTTP53 | |
| SCHEMBL7822789 | 0.71 | HSD17B3 (0.38) | HSD17B3MAPTTSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133498-A2 | AMINO-AND MERCURIO-SUBSTITUTED 4', 5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2001-09-19 | — | — | EP | claimed |
| WO-2000031081-A2 | AMINO- AND MERCURIO-SUBSTITUTED 4',5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2000-06-02 | — | — | WO | claimed |
| EP-1133498-A2 | AMINO-AND MERCURIO-SUBSTITUTED 4', 5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2001-09-19 | — | — | EP | disclosed |
| US-6255324-B1 | MICROBIOCIDES; SKIN DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-07-03 | — | — | US | disclosed |
| WO-2000031081-A2 | AMINO- AND MERCURIO-SUBSTITUTED 4',5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2000-06-02 | — | — | WO | disclosed |