Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821373 | 0.83 | KDM4E (0.33) | PPARGKDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL7670817 | 0.81 | KDM4E (0.37) | KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL7815067 | 0.79 | HSD17B10 (0.33) | KDM4EHPGDHSD17B10 | |
| SCHEMBL7816316 | 0.76 | MMP2 (0.31) | — | |
| SCHEMBL6981392 | 0.70 | RXRA (0.33) | — | |
| SCHEMBL6972568 | 0.69 | HDAC4 (0.31) | — | |
| SCHEMBL7675064 | 0.68 | CYP3A4 (0.36) | KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL7675081 | 0.64 | RXRA (0.35) | CYP3A4 | |
| SCHEMBL7998817 | 0.64 | RARA (0.35) | PPARGKDM4EHPGDHSD17B10 | |
| SCHEMBL7678262 | 0.63 | ALDH1A1 (0.38) | KDM4EHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144401-A3 | THIOCHROMANOYL CYCLOHEXENONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144401-A2 | THIOCHROMANOYL CYCLOHEXENONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000035903-A2 | THIOCHROMANOYL CYCLOHEXENONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-22 | — | — | WO | disclosed |