Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 1.00 |
| ▸ | F10 | P00742 | 2/20 | 1.00 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.67 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.67 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.67 |
| ▸ | PLAU | P00749 | 4/20 | 0.56 |
| ▸ | F2 | P00734 | 7/20 | 0.55 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.53 |
| ▸ | C1S | P09871 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL322008 | 0.98 | LOXL2 (0.95) | LOXL2F10ST14PRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL1981173 | 0.98 | LOXL2 (0.95) | LOXL2F10ST14PRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL10925118 | 0.91 | LOXL2 (0.83) | LOXL2F10ST14PRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL10919747 | 0.86 | LOXL2 (0.74) | LOXL2F10ST14PRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL10919741 | 0.86 | LOXL2 (0.74) | LOXL2F10ST14PRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL27771922 | 0.84 | LOXL2 (0.71) | LOXL2F10ST14PRSS1PRSS3 | |
| SCHEMBL10922350 | 0.83 | F2 (0.86) | LOXL2F10ST14PRSS1PRSS3 | |
| SCHEMBL2717268 | 0.82 | PRSS1 (0.70) | LOXL2F10ST14PRSS1PRSS3 | |
| SCHEMBL17887806 | 0.82 | PRMT1 (0.80) | LOXL2F10ST14PRSS1PLAU | |
| SCHEMBL7815090 | 0.81 | F10 (0.68) | LOXL2F10ST14PRSS1PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854406-B1 | TUBE FOR THE PREPARATION OF WOUND HEALANT COMPOSITION | REGEN LAB SA (CH) | 2023-07-26 | — | — | EP | claimed |
| US-11207282-B2 | Tuneable delivery of nanoparticle bound active plasmin for the treatment of thrombosis | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-12-28 | — | — | US | claimed |
| EP-3154941-B1 | SMALL MOLECULE LFA-1 INHIBITORS | ALLOCYTE PHARMACEUTICALS AG (CH) | 2021-01-20 | — | — | EP | claimed |
| US-20200261386-A1 | TUNEABLE DELIVERY OF NANOPARTICLE BOUND ACTIVE PLASMIN FOR THE TREATMENT OF THROMBOSIS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2020-08-20 | — | — | US | claimed |
| US-20190040008-A1 | SMALL MOLECULE LFA-1 INHIBITORS | ALLOCYTE PHARMACEUTICALS AG (CH) | 2019-02-07 | — | — | US | claimed |
| US-10077238-B2 | Small molecule LFA-1 inhibitors | ALLOCYTE PHARMACEUTICALS AG (CH) | 2018-09-18 | — | — | US | claimed |
| US-20180147044-A1 | TUBULAR WOVEN CONSTRUCT | TORAY INDUSTRIES, INC. (JP) | 2018-05-31 | — | — | US | claimed |
| CN-105979910-B | Artificial blood vessel | 东丽株式会社 | 2018-05-18 | — | — | CN | claimed |
| EP-3305336-A1 | TUBULAR WOVEN FABRIC STRUCTURE | Toray Industries, Inc. (JP) | 2018-04-11 | — | — | EP | claimed |
| CN-107614024-A | tubular fabric structure | 东丽株式会社 | 2018-01-19 | — | — | CN | claimed |
| US-20070179083-A1 | Covalent attachment of ligands to nucleophilic proteins guided by non-covalent binding | COVALENT BIOSCIENCE INCORPORATED | 2007-08-02 | — | — | US | claimed |
| EP-1610808-A2 | COVALENT ATTACHMENT OF LIGANDS TO NUCLEOPHILIC PROTEINS GUIDED BY NON-COVALENT BINDING | University of Texas Medical School (US) | 2006-01-04 | — | — | EP | claimed |
| EP-0869966-B1 | PRODRUGS OF THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2005-03-16 | — | — | EP | claimed |
| WO-2004087059-A2 | COVALENT ATTACHMENT OF LIGANDS TO NUCLEOPHILIC PROTEINS GUIDED BY NON-COVALENT BINDING | THE UNIVERSITY OF TEXAS (US) | 2004-10-14 | — | — | WO | claimed |
| US-6716834-B2 | ANTICOAGULANTS. | ASTRAZENECA AB (SE) | 2004-04-06 | — | — | US | claimed |
| EP-1283837-B1 | NEW THIOCHROMANE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2004-02-25 | — | — | EP | claimed |
| US-20030220317-A1 | Thiochromane derivatives and their use as thrombin inhibitors | ASTRAZENECA AB (SE) | 2003-11-27 | — | — | US | claimed |
| US-6433186-B1 | TREATMENT OF CONDITIONS WHERE INHIBITION OF THROMBIN IS REQUIRED (E.G. THROMBOSIS) OR AS ANTICOAGULANTS. | ASTRAZENECA AB (SE) | 2002-08-13 | — | — | US | claimed |
| US-20020068730-A1 | New amidino derivatives and their use as thormbin inhibitors | ASTRAZENECA AB (SE) | 2002-06-06 | — | — | US | claimed |
| EP-0377229-B1 | Use of specific properties of allergens from animal sources and methods for their isolation | LETI LAB (ES) | 1996-06-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220317-A1 | Thiochromane derivatives and their use as thrombin inhibitors | SERPINC1, F2, TFPI | LOXL2 2577/4885F10 76/4885ST14 988/4885 |
| US-11207282-B2 | Tuneable delivery of nanoparticle bound active plasmin for the treatment of thrombosis | PLAT, PLG, PLAUR | LOXL2 747/4885F10 53/4885ST14 838/4885 |
| US-10077238-B2 | Small molecule LFA-1 inhibitors | ICAM1, VCAM1, ITGB1 | LOXL2 1647/4885F10 920/4885ST14 1628/4885 |
| US-20070179083-A1 | Covalent attachment of ligands to nucleophilic proteins guided by non-covalent binding | FABP1, FPR1, ADGRF1 | LOXL2 115/4885F10 882/4885ST14 3041/4885 |
| US-20190040008-A1 | SMALL MOLECULE LFA-1 INHIBITORS | ICAM1, VCAM1, ITGB1 | LOXL2 1647/4885F10 920/4885ST14 1628/4885 |
| US-20020068730-A1 | New amidino derivatives and their use as thormbin inhibitors | SERPINC1, SERPINE1, ADAMTS1 | LOXL2 1850/4885F10 136/4885ST14 712/4885 |
| US-20200261386-A1 | TUNEABLE DELIVERY OF NANOPARTICLE BOUND ACTIVE PLASMIN FOR THE TREATMENT OF THROMBOSIS | PLAT, PLG, PLAUR | LOXL2 747/4885F10 53/4885ST14 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.