Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA4 | P22748 | 6/20 | 0.37 |
| ▸ | CA7 | P43166 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972893 | 0.83 | ALDH1A1 (0.47) | CYP2C9CYP2C19MAPTALDH1A1LMNA | |
| SCHEMBL7815260 | 0.78 | ALDH1A1 (0.49) | POLBMAPTTDP1ALDH1A1LMNA | |
| SCHEMBL30079352 | 0.77 | CKS1B (0.46) | MAPTTDP1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6864907 | 0.76 | MAPT (0.51) | CYP2C9CYP2C19POLBMAPTCA12 | |
| SCHEMBL9978927 | 0.73 | MAPT (0.61) | CYP2C9CYP2C19POLBMAPTTDP1 | |
| SCHEMBL21461553 | 0.72 | MAPT (0.38) | CYP2C9CYP2C19POLBMAPTTDP1 | |
| SCHEMBL21681245 | 0.72 | MAPT (0.38) | CYP2C9CYP2C19POLBMAPTTDP1 | |
| SCHEMBL14804540 | 0.72 | ALDH1A1 (0.58) | CYP2C9CYP2C19MAPTALDH1A1LMNA | |
| SCHEMBL14804530 | 0.72 | ALDH1A1 (0.44) | CYP2C9CYP2C19POLBMAPTTDP1 | |
| SCHEMBL7805633 | 0.72 | CTSL (0.46) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788498-B1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-1996013502-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |