Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARK4 | Q96L34 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825345 | 0.94 | KCNA5 (0.48) | MARK4TP53POLBRXFP1MAPT | |
| SCHEMBL7815265 | 0.90 | POLB (0.46) | MARK4TP53POLBPKMRXFP1 | |
| SCHEMBL8139948 | 0.85 | MAPT (0.45) | MARK4TP53POLBMAPTKMT2A | |
| SCHEMBL7811288 | 0.83 | KCNA5 (0.49) | TP53POLBMAPTKMT2AHTR6 | |
| SCHEMBL7825347 | 0.79 | SMN1; SMN2 (0.45) | MARK4TP53POLBPKM | |
| SCHEMBL7814384 | 0.79 | HTR6 (0.45) | TP53POLBPKMMAPTHTR6 | |
| SCHEMBL7854322 | 0.79 | LMNA (0.44) | TP53MAPTHTR6 | |
| SCHEMBL7818699 | 0.78 | TP53 (0.52) | TP53RXFP1MAPTHTR6 | |
| SCHEMBL7968902 | 0.76 | HTR6 (0.42) | POLBL3MBTL1KMT2AHTR6 | |
| SCHEMBL7968903 | 0.76 | HTR6 (0.42) | POLBL3MBTL1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077948-A1 | NOVEL 1,2,5-TRISUBSTITUTED 1,2-DIHYDRO-INDAZOL-3-ONES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICAMENT | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-02-28 | — | — | EP | claimed |
| US-6180637-B1 | THERAPY FOR PARKINSON, ALZHEIMER DISEASE | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-01-30 | — | — | US | claimed |
| WO-1999058504-A9 | NOVEL 1,2,5-TRISUBSTITUTED 1,2-DIHYDRO-INDAZOL-3-ONES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICAMENT | DRESDEN ARZNEIMITTEL (DE) | 2000-02-03 | — | — | WO | claimed |
| WO-1999058504-A1 | NOVEL 1,2,5-TRISUBSTITUTED 1,2-DIHYDRO-INDAZOL-3-ONES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICAMENT | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-11-18 | — | — | WO | claimed |
| US-6180637-B1 | THERAPY FOR PARKINSON, ALZHEIMER DISEASE | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-01-30 | — | — | US | disclosed |