Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968903 | 1.00 | HTR6 (0.42) | HTR6POLBL3MBTL1ALDH1A1KCNA5 | |
| SCHEMBL7818699 | 0.78 | TP53 (0.52) | HTR6 | |
| SCHEMBL7854322 | 0.78 | LMNA (0.44) | HTR6ALDH1A1PPARGLMNA | |
| SCHEMBL7814384 | 0.78 | HTR6 (0.45) | HTR6POLBLMNA | |
| SCHEMBL7815264 | 0.76 | MARK4 (0.51) | HTR6POLBL3MBTL1KMT2A | |
| SCHEMBL7978978 | 0.75 | TP53 (0.52) | HTR6LMNA | |
| SCHEMBL7814773 | 0.74 | HTR6 (0.41) | HTR6POLBALDH1A1PPARGLMNA | |
| SCHEMBL6962715 | 0.74 | HTR6 (0.41) | HTR6POLBL3MBTL1ALDH1A1PPARG | |
| SCHEMBL6962722 | 0.74 | HTR6 (0.41) | HTR6POLBL3MBTL1ALDH1A1PPARG | |
| SCHEMBL7811288 | 0.73 | KCNA5 (0.49) | HTR6POLBALDH1A1KCNA5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180637-B1 | THERAPY FOR PARKINSON, ALZHEIMER DISEASE | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-01-30 | — | — | US | claimed |
| US-6180637-B1 | THERAPY FOR PARKINSON, ALZHEIMER DISEASE | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-01-30 | — | — | US | disclosed |